منابع مشابه
The Aging Human Brain
The human brain weighs on average about three pounds, consists of 200 billion cells. Surprisingly, there are only two categories of brain cells, neurons and glia, but more than 50 different cellular subtypes. Nerve cells or neurons are specialized cells that are electrically excitable, and processes and transmit information to other neurons and cells through electrochemical signaling v...
متن کاملDiffusion changes in the aging human brain.
BACKGROUND AND PURPOSE Quantifying changes in the human brain that occur as part of normal aging may help in the diagnosis of diseases that affect the elderly and that cause structural changes in the brain. We sought to assess diffusion changes that are inherently related to brain structure during aging. METHODS MR scans were obtained from 11 healthy volunteers and 27 patients (ages 26 to 86 ...
متن کاملDystrophic microglia in the aging human brain.
We have studied microglial morphology in the human cerebral cortex of two nondemented subjects using high-resolution LN-3 immunohistochemistry. Several abnormalities in microglial cytoplasmic structure, including deramification, spheroid formation, gnarling, and fragmentation of processes, were identified. These changes were determined to be different from the morphological changes that occur d...
متن کاملPET Imaging of Tau Deposition in the Aging Human Brain
Tau pathology is a hallmark of Alzheimer's disease (AD) but also occurs in normal cognitive aging. Using the tau PET agent (18)F-AV-1451, we examined retention patterns in cognitively normal older people in relation to young controls and AD patients. Age and β-amyloid (measured using PiB PET) were differentially associated with tau tracer retention in healthy aging. Older age was related to inc...
متن کاملHuman Ecology: Industrial Ecology
Industrial Ecology aims to inform decision making about the environmental impacts of industrial production processes by tracking and analyzing resource use and flows of industrial products, consumer products and wastes. Quantifying the patterns of use of materials and energy in different societies is one area of research in Industrial Ecology. An extensive literature is devoted in particular to...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2011
ISSN: 0003-9942
DOI: 10.1001/archneurol.2011.157